Neuriva Plus Review 2026

James BevanJames BevanUpdated November 5, 2026
Neuriva Plus bottle, 30 capsules, official product image

Neuriva Plus is Schiff's one-capsule brain health supplement, with coffee fruit extract, phosphatidylserine and three B vitamins, sold everywhere from Amazon to the pharmacy shelf. But does it have enough of each to match its research, and was this formula ever tested? To find out, we've checked every dose against the published studies, read the trial Neuriva cites and looked at what buyers have to say.

Quick verdict

Our scientific audit

5.4/ 10

Buyer rating

8.6/ 10
  • Price per servingNo brand-site price
  • Doses in range1 of 2
  • CaffeineNone
  • Money-back guaranteeNone
  • Third-party testingUnverified, no report or certification
  • Servings per bottle30

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In this review

What's good, and what isn't

Pros

  • 200 mg of coffee fruit extract, the dose used in its most recent trial
  • Every amount is printed, in one capsule a day
  • Easy to find at most US pharmacies and big-box stores

Cons

  • 100 mg of phosphatidylserine is a third of the 300 mg used in its trials
  • Neuriva's only product trial tested Neuriva Original, not Plus
  • No lab report or certification is published, and there's no brand money-back guarantee

Why Neuriva Plus scored 5.4 out of 10 in our scientific audit

  • Dose fit40%67

    Coffee fruit extract (Neurofactor) at 200 mg earns full credit. Phosphatidylserine is 100 mg against 300 mg, so it earns a third. The B vitamins aren't scored.

  • Evidence30%32

    Each ingredient's evidence counts in proportion to its dose credit. Coffee fruit's research is small and mostly funded by its maker, and phosphatidylserine only earns a third of its credit at this dose.

  • Transparency20%90

    Every amount is printed and nothing sits in a blend. It loses points because we read the label from the brand's image, and the brand's versions disagree on the directions and other ingredients.

  • No third-party testing, certificate of analysis or certification program listing found.

Worked out under method audit-v2.0. How the rating is built

Score history
  1. Nov 5, 2026 First audit published (5.4)

    We checked the label, compared each dose with the human research and published the review.

Neuriva Plus has two ingredients we score, and they pull in opposite directions. The 200 mg of coffee fruit extract is right on the dose used in its most recent trial, so it gets full credit. The 100 mg of phosphatidylserine is a third of the 300 mg a day in the trials we use as its benchmark, and that's where most of the formula score goes. The three B vitamins are there as nutrition, so we don't score them.

Evidence is weak too. The coffee fruit research is small and almost all of it was paid for by the company that makes the extract, and phosphatidylserine only earns a third of its credit at this dose. Every amount is printed, which keeps transparency high, but testing scores zero, because we found no lab report or certification for Neuriva Plus.

The claims, checked

Neuriva Plus bottle, 30 capsules, official product image
Official product image. View official source
Neuriva Plus supplement facts. 1 capsule per serving. Vitamin B6 1.7 mg, folate 680 mcg DFE (400 mcg folic acid), vitamin B12 2.4 mcg, coffee fruit extract 200 mg, phosphatidylserine 100 mg
Official supplement facts label. View official source

The label lists five ingredients in one capsule, with 30 capsules in a bottle, and nothing is hidden in a blend.1 The directions are one capsule a day. The product page says not to take it if you're pregnant, breastfeeding, on medication or managing a medical condition unless your doctor agrees, and it notes that the capsules contain soy.2 Neuriva calls the formula decaffeinated, so there's no meaningful caffeine in it.

“15+ clinical studies on ingredients, 1 full product clinical”

Partly

The one full product trial is real, but it tested Neuriva Original, not Plus.3 That trial gave 138 adults with memory complaints 100 mg of coffee fruit and 100 mg of phosphatidylserine for 42 days.4 Plus has twice the coffee fruit and adds B vitamins, so nobody has tested this exact formula. The trial also had two main measures, and the one tied to Neuriva's BDNF story, blood levels of the protein, came out no different from placebo.

“24% in memory, 30.5% in focus, and 23% improvement in accuracy”

Doesn't hold up

These figures are on Neuriva's clinical page, presented as results from the Original trial.3 We couldn't find them anywhere in the published paper, which reports the differences from placebo as statistical results on individual computer tasks rather than percentages.4 Several other measures in the same trial, including a memory questionnaire, showed no benefit. Even taken at face value, the figures describe a different product from the one in this bottle.

“Clinical studies have shown that coffee cherry (Neurofactor) and plant-source phosphatidylserine enhance brain health”

Partly

There are human trials of coffee fruit extract, and the newest one used Neuriva Plus's 200 mg.5 They're small, though, and the extract's maker paid for nearly all of them. The phosphatidylserine claim is weaker. The plant form at three times this dose didn't beat placebo in older adults with memory complaints.6

“Third-party testing”

Unverified

Neuriva doesn't claim third-party testing on the product page, and we found no certificate of analysis, lab report or certification program listing for Neuriva Plus.2 That doesn't mean anything is wrong with it, but there's nothing for you to check.

Neuriva's "clinically proven" advertising has also been in court. A class action over those claims was settled for up to about 8 million dollars. A federal appeals court then threw out the settlement in 2023, ruling that the named buyers had no standing to ask for a change in the advertising.7 A second class action, filed in 2025, covers Original, Plus, Ultra and the gummies and alleges that the brain-health and "clinically tested" claims are false. It's still pending, and nothing has been proven.8

What's inside, audited

2 ingredients checked, 1 within range, 1 short.

Within range (coffee fruit extract). Short (phosphatidylserine).

Coffee Fruit ExtractWithin range

Neurofactor (named on the product page) · Preliminary evidence

200 mg
200 mg
0200 mg

Doses used in studies that showed a benefit

Neuriva Plus has 200 mg, the daily dose used in studies that showed a benefit.5

Study dose benchmark from Robinson 2024, 200 mg5

Coffee fruit extract is the whole coffee cherry, dried and decaffeinated, sold to brands as Neurofactor. The 200 mg here matches a 28-day trial in adults aged 40 to 65 that found better accuracy on a working memory task than placebo.5 That trial was run remotely, and VDF FutureCeuticals, which makes and patents the extract, paid for it. The earlier studies Neuriva cites mostly used 100 mg, including one where a single dose raised a brain-growth protein called BDNF in the blood of small groups of volunteers.93 Neuriva Plus has twice the amount of Neuriva Original, and that's the main difference between the two.2

Phosphatidylserine200 mg short

source not stated (contains soy) · Moderate evidence

100 mg
100 mg
0300 mg

Doses used in studies that showed a benefit

Neuriva Plus has 100 mg. The study dose we use as this ingredient's benchmark is 300 mg, so it's 200 mg short.10

Study dose benchmark from Crook 1991, 100 mg three times a day, 12 weeks10

Phosphatidylserine is 100 mg, against the 300 mg a day in the trial we use as its benchmark, which improved memory in older adults over 12 weeks.10 That trial used phosphatidylserine from cow brain, which isn't sold anymore. The label doesn't say where Neuriva's comes from, although the product page calls it plant sourced and the box warns that it contains soy.2 A trial of soy phosphatidylserine at 300 and 600 mg a day in older adults found no difference from placebo,6 so even the full dose of the plant form is far from settled.

Also on the label are vitamin B6 1.7 mg, folate 400 mcg, vitamin B12 2.4 mcg. These have no cognitive dose range for people who aren't deficient, so they don't count toward the formula score.

How we choose the studies and set these ranges

Vitamin B6, folate and B12 are each at or above 100 percent of the daily value, which is about what a multivitamin gives you. They help if you're short of them, but there's no reason to expect them to sharpen focus in someone who isn't.

Compare it yourself

Neuriva Plus against its closest matches

ProductNeuriva Plus bottle, official product imageNeuriva PlusThis review
Scientific audit5.4/10
Buyer rating8.6/10
Price per servingNo brand-site price
Doses of Neuriva Plus's ingredients
Phosphatidylserine100 mgsource not stated (contains soy)200 mg below the study dose benchmark
Coffee Fruit Extract200 mgNeurofactor (named on the product page)At or above the study dose benchmark

The products that share the most cognitive ingredients with Neuriva Plus are shown first. Any product sharing at least two can be added.

If coffee fruit is what interests you, the extract is sold on its own, and Neuriva Plus doesn't add much to it beyond a low dose of phosphatidylserine and some B vitamins. For a fuller formula, Mind Lab Pro has citicoline, bacopa, lion's mane and more for $2.30 a serving, and Transparent Labs Cognition scores higher with citicoline, rhodiola and a little more phosphatidylserine, at 140 mg.

Price and where to buy

Schiff doesn't sell Neuriva Plus itself. Its product page points you to a store finder instead of a basket, so there's no brand price for us to show.2 You'll find it at Amazon, Walmart, Target, iHerb and most large pharmacies, and the price moves with the store and any multipack deal, so compare a few before buying.

What other reviewers say

Illuminate Labs doesn't recommend Neuriva, and calls Plus not worth its higher price over Original.11 HighYa, in an older review that lists the same doses as today's label, gave it 3 out of 5 and called it "moderately priced, has mediocre reviews, and lacks robust research."12 Several other pages that rank for Neuriva describe an older formula or the gummies, or still describe the 2021 settlement as final, but the appeals court vacated its approval in 2023.7

What buyers report

4.34.3 out of 5 starsWeighted average of 40,153 ratings on Amazon, iHerb, Target and Walmart
Amazon4.3/5 · 37,828 ratings
iHerb4.7/5 · 89 ratings
Target, its own reviews3.9/5 · 15 ratings
Walmart4.5/5 · 2,221 ratings

Safety notes

The product page says to check with your doctor first if you're pregnant, breastfeeding, taking medication or managing a medical condition.2 The capsules contain soy, so skip it if you're allergic. We're researchers, not doctors.

Final thoughts

Neuriva Plus is an easy one-capsule supplement from a big brand, with every amount printed and the coffee fruit at the dose its latest trial used. What holds it back is how much it leans on research it hasn't done. The one product trial tested Neuriva Original, the coffee fruit studies were funded by the extract's maker, and the phosphatidylserine is a third of its studied dose.

If you want to try coffee fruit extract in a capsule you can pick up anywhere, Neuriva Plus is a reasonable way to do it. If you want a formula with more ingredients at their studied doses, there are better options for the money.

FAQ

What's the difference between Neuriva Plus and Neuriva Original?
Plus has 200 mg of coffee fruit extract, twice Original's 100 mg, and adds vitamin B6, folate and B12. Both have 100 mg of phosphatidylserine.
Does Neuriva Plus contain caffeine?
Neuriva describes the coffee fruit extract as decaffeinated, so there's no meaningful caffeine in it.
How do you take Neuriva Plus?
One capsule a day, according to the product page.
Has Neuriva Plus been clinically tested?
Not as a finished product. Neuriva's only product trial tested Neuriva Original, which has half the coffee fruit and no B vitamins.
Is Neuriva Plus third-party tested?
We found no lab report, certificate of analysis or certification for it.
Where can you buy Neuriva Plus?
At retailers such as Amazon, Walmart, Target, iHerb and large pharmacies. Schiff doesn't sell it directly.
Was there a Neuriva lawsuit?
Yes. An appeals court threw out a settlement over its "clinically proven" advertising in 2023, and a second class action filed in 2025 is still pending. Nothing has been proven against the company.

Sources

12 sources cited

  1. Schiff (RB Health). Neuriva Plus supplement facts image on the product page. 1 capsule a serving, vitamin B6 (pyridoxine hydrochloride) 1.7 mg, folate 680 mcg DFE (400 mcg folic acid), vitamin B12 (cyanocobalamin) 2.4 mcg, coffee fruit extract (Coffea arabica) 200 mg, phosphatidylserine 100 mg. Accessed Nov 5, 2026. Label image
  2. Schiff (RB Health). Neuriva Plus product page. "2X the amount of Neurofactor" compared with Neuriva Original, "plant sourced Phosphatidylserine", "Clinical studies have shown that coffee cherry (Neurofactor) and plant-source phosphatidylserine enhance brain health", Neurofactor "clinically tested to increase levels of the neuroprotein BDNF", directions one capsule daily, caution for pregnancy, breastfeeding, medication or a medical condition, contains soy, a "Where to buy" widget and no price, review widget 4.2 from 101. Accessed Nov 5, 2026. schiffvitamins.com
  3. Schiff (RB Health). Neuriva clinical page. "15+ clinical studies on ingredients, 1 full product clinical", and for Neuriva Original "24% in memory, 30.5% in focus, and 23% improvement in accuracy". Accessed Nov 5, 2026. schiffvitamins.com/pages/neuriva-clinical
  4. Doma KM, et al. A randomized, double-blind, placebo-controlled, parallel study investigating the efficacy of a whole coffee cherry extract and phosphatidylserine formulation on cognitive performance of healthy adults with self-perceived memory problems. Neurol Ther, 2023. Neuriva (100 mg coffee cherry extract and 100 mg phosphatidylserine) for 42 days, 138 adults aged 40 to 65, funded by Reckitt, four authors Reckitt employees. No difference from placebo on BDNF, the Everyday Memory Questionnaire or Go/No-Go. PMID 36929344
  5. Robinson JL, et al. Whole coffee cherry extract improves working memory and response inhibition. Acute and longitudinal results from a remote, randomized, double-blind, placebo-controlled clinical trial. Nutrients, 2024. 200 mg a day for 28 days, adults aged 40 to 65, sponsored by VDF FutureCeuticals, which makes the extract. PMID 39064791
  6. Jorissen BL, et al. The influence of soy-derived phosphatidylserine on cognition in age-associated memory impairment. Nutr Neurosci, 2001. 300 or 600 mg a day for 12 weeks, 120 older adults, no significant differences from placebo. PMID 11842880
  7. Williams v. Reckitt Benckiser LLC, No. 22-11232 (11th Cir. Apr. 12, 2023). The court vacated the district court's approval of the class settlement over Neuriva's "clinically proven" advertising and remanded, finding the named plaintiffs lacked standing for injunctive relief. Accessed Nov 5, 2026. ca11.uscourts.gov
  8. Truth in Advertising. Class action, Neuriva. Timmons et al. v. Reckitt Benckiser LLC and RB Health (US) LLC, 25-cv-12192, N.D. Ill. (Oct. 2025), covering Neuriva Original, Plus, Ultra and the gummies, allegations of false memory and focus claims and "clinically tested" claims, status pending. Accessed Nov 5, 2026. truthinadvertising.org
  9. Reyes-Izquierdo T, et al. Modulatory effect of coffee fruit extract on plasma levels of brain-derived neurotrophic factor in healthy subjects. Br J Nutr, 2013. A single 100 mg dose raised plasma BDNF, small groups. PMID 23312069
  10. Crook TH, et al. Effects of phosphatidylserine in age-associated memory impairment. Neurology, 1991. 100 mg of bovine cortex phosphatidylserine three times a day for 12 weeks, 149 adults. PMID 2027477
  11. Graber T, Cook C. Neuriva review. Illuminate Labs, last updated Oct 28, 2026. "We do not currently recommend Neuriva", Plus described as not worth the higher price. Accessed Nov 5, 2026. illuminatelabs.org
  12. Dugarte A. Neuriva reviews. HighYa, updated Jun 25, 2020. Rating 3.0, "moderately priced, has mediocre reviews, and lacks robust research". Accessed Nov 5, 2026. highya.com

Where this data comes from

Third-party testing
None claimed or published
How we reviewed it
Label and evidence audit
Refund policy
No brand guarantee, so returns follow the store you buy from

Our scoring method, weights, and the rules that keep affiliate money away from scores are documented on the editorial process page.

Top Rated Nootropics is an independent research and review platform. We are passionate supplement researchers, not medical professionals. Always consult a qualified healthcare provider before starting any supplement regimen. These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.